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Article

Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene.

Developmental biology - 25 Aug 1996

Matsui M, Oshima M, Oshima H, Takaku K, Maruyama T, Yodoi J, Taketo M M

Abstract excerpt

Thioredoxins belong to a widely distributed group of small proteins with strong reducing activities mediated by a consensus redox-active dithiol (Cys-Gly-Pro-Cys). Thioredoxin was first isolated as a hydrogen donor for enzymatic synthesis of deoxyribonucleotides by ribonucleotide reductase in Escherichia coli. Recent studies have revealed a variety of roles that thioredoxin plays in transcription, growth control,...

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Identifiers

PMID: 8812119
DOI: 10.1006/dbio.1996.0208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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