Interchromosomal transfer of epigenetic states in Ascobolus: transfer of DNA methylation is mechanistically related to homologous recombination.

doi:10.1016/s0092-8674(00)80161-0

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Article

Interchromosomal transfer of epigenetic states in Ascobolus: transfer of DNA methylation is mechanistically related to homologous recombination.

Cell - 20 Sept 1996

Colot V, Maloisel L, Rossignol J L

Abstract excerpt

The transfer of methylation between alleles represents a plausible epigenetic mutational mechanism to explain loss of imprinting in mammals and paramutation in plants. Here, we have exploited advantages unique to the fungus Ascobolus immersus to obtain direct experimental evidence that methylatio...

Topics

Alleles
Ascomycota
Crosses, Genetic
DNA Methylation
DNA, Fungal
Gene Conversion
Genes, Fungal
Genomic Imprinting
Haploidy
Meiosis
Models, Genetic
Polymorphism, Genetic
Recombination, Genetic
Sister Chromatid Exchange

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