Article
Suppression of crossing-over by DNA methylation in Ascobolus.
Genes & development - 1 May 1998
Maloisel L, Rossignol J L
Abstract excerpt
Homologous recombination between dispersed DNA repeats creates chromosomal rearrangements that are deleterious to the genome. The methylation associated with DNA repeats in many eukaryotes might serve to inhibit homologous recombination and play a role in preserving genome integrity. We have tested the hypothesis that DNA methylation suppresses meiotic recombination in the fungus Ascobolus immersus. The natural...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
