Article
A recombinationally repressed region between mat2 and mat3 loci shares homology to centromeric repeats and regulates directionality of mating-type switching in fission yeast.
Genetics - 1 Aug 1997
Grewal S I, Klar A J
Abstract excerpt
Cells of the fission yeast Schizosaccharomyces pombe switch mating type by replacing genetic information at the transcriptionally active mat1 locus with sequences copied from one of two closely linked silent loci, mat2-P or mat3-M. By a process referred to as directionality of switching, cells predominantly switch to the opposite mat1 allele; the mat1-P allele preferentially recombines with mat3, while mat1-M...
Topics
- Base Sequence
- Chromosome Mapping
- Cloning, Molecular
- DNA, Fungal
- Gene Deletion
- Genes, Fungal
- Genes, Mating Type, Fungal
- Genes, Switch
- Genome, Fungal
- Models, Genetic
- Molecular Sequence Data
- Phenotype
- Recombination, Genetic
- Schizosaccharomyces