Article
Epimutation of repeated genes in Ascobolus immersus.
The EMBO journal - 1 Dec 1992
Rhounim L, Rossignol J L, Faugeron G
Abstract excerpt
Ascobolus immersus artificial gene repeats were shown previously to be subject premeiotically to both cytosine methylation and inactivation. We studied sexual progenies of strains harbouring two wild type copies of the endogenous met2 gene lying either in tandem array or at ectopic unlinked positions, by (i) investigating the methylation status, (ii) searching for mutations and (iii) analysing the inheritance of...
Topics
- Acetyltransferases
- Ascomycota
- Blotting, Southern
- Cloning, Molecular
- DNA, Fungal
- Escherichia coli
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Meiosis
- Methylation
- Multigene Family
- Mutation