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Article

A meiotic gene conversion gradient opposite to the direction of transcription.

Nature - 10 Sept 1992

Malone R E, Bullard S, Lundquist S, Kim S, Tarkowski T

Abstract excerpt

Genetic recombination involves classical crossing-over and gene conversion (aberrant segregation). In fungi that produce an ascus containing four spores, a gene conversion event is manifested as 3:1 or 1:3 (or more rarely 4:0 or 0:4) segregations, in contrast to the normal mendelian 2:2 segregation. Polarity is one of the properties of gene conversion; in almost all cases the frequency of conversion exhibits a...

Topics

Alleles
Chromosome Mapping
Gene Conversion
Genes, Fungal
Meiosis
Mutagenesis, Site-Directed
Polymorphism, Restriction Fragment Length
Promoter Regions, Genetic
Saccharomyces cerevisiae
Transcription, Genetic

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PMID: 1355857
DOI: 10.1038/359154a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1355857-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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