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Article

Search for unstable DNA in schizophrenia families with evidence for genetic anticipation.

American journal of human genetics - 1 Oct 1996

Petronis A, Bassett A S, Honer W G, Vincent J B, Tatuch Y, Sasaki T, Ying D J, Klempan T A, Kennedy J L

Abstract excerpt

Evidence for genetic anticipation has recently become an important subject of research in clinical psychiatric genetics. Renewed interest in anticipation was evoked by molecular genetic findings of a novel type of mutation termed "unstable DNA." The unstable DNA model can be construed as the "best fit" for schizophrenia twin and family epidemiological data. We have performed a large-scale Southern blot...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8808607
PMCID: PMC1914813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Search for unstable DNA in schizophrenia families with evidence for genetic anticipation.PMID 8808607Read ↗

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Heritable trinucleotide repeats and neurological disorders.Semantic proximity Read ↗

Anticipation and repeat expansion in bipolar disorder.Semantic proximity Read ↗

Hereditary unstable DNA: a new explanation for some old genetic questions?Semantic proximity Read ↗

Expansion of 50 CAG/CTG repeats excluded in schizophrenia by application of a highly efficient approach using repeat expansion detection and a PCR screening set.Semantic proximity Read ↗

Unstable DNA may be responsible for the incomplete penetrance of the myotonic dystrophy phenotype.Semantic proximity Read ↗

Long repeat tracts at SCA8 in major psychosis.Semantic proximity Read ↗

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