Article
Hereditary unstable DNA: a new explanation for some old genetic questions?
Lancet (London, England) - 3 Aug 1991
Sutherland G R, Haan E A, Kremer E, Lynch M, Pritchard M, Yu S, Richards R I
Abstract excerpt
Fragile X syndrome, associated with the fragile X chromosome, is the most common cause of familial mental retardation. The condition is characterised by a heritable DNA sequence that consists of an abnormal number of CCG repeats, and which is unstable in both mitosis and meiosis. We suggest that such heritable unstable DNA sequences could be present in other parts of the genome and that these might explain a...
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