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Article

Unstable repeat expansion in major psychiatric disorders: two decades on, is dynamic DNA back on the menu?

Psychiatric genetics - 1 Aug 2016

Vincent John B

Abstract excerpt

For a period in the mid-1990s, soon after the discovery of the involvement of trinucleotide repeat expansions in fragile-X syndrome (both A and E), Huntington's disease, myotonic dystrophy, and a number of hereditary ataxias, there was a clear sense that this new disease mechanism might provide answers for psychiatric disorders. Given the then failures to replicate initial genetic linkage findings for...

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PMID: 27270050
DOI: 10.1097/YPG.0000000000000141

Genes

TCF4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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