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Article

Unstable genes--unstable mind?

The American journal of psychiatry - 1 Feb 1995

Petronis A, Kennedy J L

Abstract excerpt

OBJECTIVE: Over the past 3 years, reports of DNA alteration in myotonic dystrophy, fragile X syndrome (types A and E), Kennedy's disease, Huntington's disease, spinocerebellar ataxia type 1, and dentatorubral-pallidoluysian atrophy have identified a new class of human mutation, referred to as trinucleotide repeat amplification. All available evidence suggests that this unstable trinucleotide repeat DNA is the...

Topics

Adult
Age of Onset
Bipolar Disorder
Child
DNA
Diseases in Twins
Family
Female
Genetic Heterogeneity
Genetic Linkage
Humans
Male
Mental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Genetic

Mutation

Severity of Illness Index

Twins, Dizygotic

Twins, Monozygotic

Source

Identifiers

PMID: 7840347
DOI: 10.1176/ajp.152.2.164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7840347-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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