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Article

Carcinoma cell lines become sensitive to DNA-damaging agents by the expression of the adenovirus E1A gene.

Oncogene - 5 Sept 1996

Sánchez-Prieto R, Quintanilla M, Cano A, Leonart M L, Martin P, Anaya A, Ramón y Cajal S

Abstract excerpt

Squamous cell carcinomas can show different oncogenic alterations, histological patterns, and an unpredictable clinical behavior. We previously reported that the adenovirus E1a gene may induce sensitivity to DNA-damaging agents in mouse keratinocytes. In order to study whether E1a expression could be used as a therapeutic agent in different malignant cell lines carrying mutations on the p53 gene and other...

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PMID: 8806698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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