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Article

The intracellular fate of apolipoprotein E is tau dependent and apoe allele-specific.

Neuroreport - 10 Apr 1996

Lovestone S, Anderton B H, Hartley C, Jensen T G, Jorgensen A L

Abstract excerpt

The apolipoprotein E (apoE) gene has been identified as a susceptibility gene for Alzheimer's disease, although the mechanism whereby apoE exerts this effect has not been determined. The aim of this study was to examine the intracellular fate of apoE and we demonstrate that in mammalian cells-transiently expressing tau and the low density lipoprotein receptor, apoE is taken up from cerebrospinal fluid (CSF) and...

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Source

Identifiers

PMID: 8804040
DOI: 10.1097/00001756-199604100-00010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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