Article
Apolipoprotein E and beta A4-amyloid: signals and effects.
Biochemical Society symposium - 1 Jan 2001
Ohm T G, Hamker U, Cedazo-Minguez A, Röckl W, Scharnagl H, März W, Cowburn R, Müller W, Meske V
Abstract excerpt
In humans, the apolipoprotein E gene (APOE) is polymorphic with the alleles APOE epsilon 2, 3 and 4 coding for apolipoproteins (Apo) E2, 3 and 4. Apart from age, the APOE epsilon 4 allele represents the most important risk factor in sporadic Alzheimer's disease (AD). Compared to APOE epsilon 3 ho...
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