Article
The sigma subunit of Escherichia coli RNA polymerase senses promoter spacing.
Proceedings of the National Academy of Sciences of the United States of America - 20 Aug 1996
Dombroski A J, Johnson B D, Lonetto M, Gross C A
Abstract excerpt
The promoters recognized by sigma 70, the primary sigma of Escherichia coli, consist of two highly conserved hexamers located at -10 and -35 bp from the start point of transcription, separated by a preferred spacing of 17 bp. sigma factors have two distinct DNA binding domains that recognize the...
Topics
- Base Sequence
- Binding Sites
- DNA-Binding Proteins
- DNA-Directed RNA Polymerases
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Promoter Regions, Genetic
- Protein Binding
- Sigma Factor
- Transcription, Genetic