Article
Detection of ras gene mutations in perioperative peripheral blood with pancreatic adenocarcinoma.
Japanese journal of cancer research : Gann - 1 Aug 1996
Nomoto S, Nakao A, Kasai Y, Harada A, Nonami T, Takagi H
Abstract excerpt
Surgeons wish to know of any correlation between an operation and the incidence of metastasis. In perioperative periods, pancreatic cancer cells were identified by detecting mutant K-ras gene by two-step PCR and RFLP analysis in blood samples taken from peripheral blood. In no case was K-ras point mutation detected in blood before operation, although the mutant hand was observed in all cases at the time the...
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