Article
[Detection of point mutation of Kirsten ras oncogene in pancreatic carcinoma by polymerase chain reaction].
Nihon Geka Gakkai zasshi - 1 Apr 1991
Motojima K, Kohara N, Furui J, Terada M, Tsunoda T, Nagata Y, Urano K
Abstract excerpt
Regarding to the pancreatic cancer, outcomes of the patients surgically treated have been poor. By using polymerase chain reaction (PCR), paraffin-embedded specimens of the pancreatic carcinoma were confined point mutation in Kirsten (K)-ras codon 12. Then, incidence and type of point mutation of this oncogene and correlative studies with stage, T or N factor of pancreatic cancer were analysed. Extremely high...
Topics
- Codon
- Genes, ras
- Humans
- Mutation
- Neoplasm Staging
- Pancreatic Neoplasms
- Polymerase Chain Reaction
