Article
KRAS mutations in pancreatic cancer: could we talk about a risk factor for the development of thromboembolic phenomena?
Revista espanola de enfermedades digestivas - 1 Apr 2024
Gutiérrez Pérez César, Blanco Abad Carmen, Hontoria Bautista Gadea, Saiz López Patricia, Rodríguez Ledesma Inmaculada, Espinosa Cabria Noelia, Ramos Reguera Irene, López Muñoz Ana María
Abstract excerpt
The oncogenic KRAS mutation is associated with increased tissue factor expression and thus hypercoagulability. In this regard, numerous studies published in the last decade have shown that KRAS mutations are an important risk factor for the development of thromboembolic phenomena in neoplasms of the digestive tract, such as colorectal cancer. On the other hand, some recently published studies suggest that KRAS...
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