Article
Pancreatic cancer after remote peptic ulcer surgery.
Journal of clinical pathology - 1 May 2002
Tascilar M, van Rees B P, Sturm P D J, Tytgat G N J, Hruban R H, Goodman S N, Giardiello F M, Offerhaus G J A, Tersmette A C
Abstract excerpt
BACKGROUND: Peptic ulcer surgery may carry an increased risk for pancreatic cancer development. Molecular analysis of K-ras codon 12, frequently mutated in conventional pancreatic cancers, might provide insight into the aetiological mechanisms. METHODS: The relative risk of pancreatic cancer was computed by multivariate and person-year analysis in a cohort of 2633 patients who had undergone gastrectomy. Lung...
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