Article
Clinical significance of K-Ras mutations in intraoperative tumor drainage blood from patients with colorectal carcinoma.
Annals of surgical oncology - 1 Jun 2001
Etoh T, Ueo H, Inoue H, Sato K, Utsunomiya T, Barnard G F, Kitano S, Mori M
Abstract excerpt
BACKGROUND: Recurrent and metastatic carcinoma of the colorectum remains a major problem. This may be ascribed to the presence of micrometastasis at diagnosis. The purpose of this study was to analyze prospectively the clinical value of detecting K-ras mutations in the perioperative circulating blood from patients with colorectal carcinoma. METHODS: Twenty-four patients whose tumor carried mutations in codon 12...
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