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Article

Sequence effects on RNA bulge-induced helix bending and a conserved five-nucleotide bulge from the group I introns.

Biochemistry - 10 Sept 1996

Luebke K J, Tinoco I

Abstract excerpt

Bulge loops introduce bends in RNA double helices. Thus, a role for bulge loops in the tertiary folding of RNA is to orient helical elements. The location, size, and sequence of a five-nucleotide bulge are conserved in many of the self-splicing group I introns. We have used gel electrophoretic analysis of helix bending to test the hypothesis that this bulge loop is conserved to control the angle between the...

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PMID: 8794748
DOI: 10.1021/bi960914r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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