Sequence effects on RNA bulge-induced helix bending and a conserved five-nucleotide bulge from the group I introns.

doi:10.1021/bi960914r

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Article

Sequence effects on RNA bulge-induced helix bending and a conserved five-nucleotide bulge from the group I introns.

Biochemistry - 10 Sept 1996

Luebke K J, Tinoco I

Abstract excerpt

Bulge loops introduce bends in RNA double helices. Thus, a role for bulge loops in the tertiary folding of RNA is to orient helical elements. The location, size, and sequence of a five-nucleotide bulge are conserved in many of the self-splicing group I introns. We have used gel electrophoretic an...

Topics

Animals
Base Sequence
Conserved Sequence
DNA Primers
DNA-Directed RNA Polymerases
Electrophoresis, Polyacrylamide Gel
Introns
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA, Double-Stranded
RNA, Protozoan
Tetrahymena thermophila
Viral Proteins

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