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Article

Structure of the P1 helix from group I self-splicing introns.

Journal of molecular biology - 14 Jul 1995

Allain F H, Varani G

Abstract excerpt

The upstream cleavage site of group I self-splicing introns is identified by an absolutely conserved U.G base-pair within a double helix. Mutant introns with a wobble C.A substitute are catalytically active, but all other combinations of nucleotides at these positions abolish splicing, suggesting that an unusual RNA structure generated by the wobble pair is recognized by the catalytic intron core. The solution...

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Source

Identifiers

PMID: 7608979
DOI: 10.1006/jmbi.1995.0381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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