Article
X chromosome inactivation patterns correlate with fetal-placental anatomy in monozygotic twin pairs: implications for immune relatedness and concordance for autoimmunity.
Molecular medicine (Cambridge, Mass.) - 1 Nov 1994
Trejo V, Derom C, Vlietinck R, Ollier W, Silman A, Ebers G, Derom R, Gregersen P K
Abstract excerpt
BACKGROUND: Monozygotic (MZ) twinning is a poorly understood phenomenon that may result in subtle biologic differences between twins, despite their identical inheritance. These differences may in part account for discordant expression of disease in MZ twin pairs. Due to their stochastic nature, d...
Topics
- Autoimmune Diseases
- Base Sequence
- Deoxyribonuclease HpaII
- Diseases in Twins
- Dosage Compensation, Genetic
- Female
- Fetofetal Transfusion
- Genetic Variation
- Humans
- Infant, Newborn
- Molecular Sequence Data