Article
MZ female twins discordant for X-linked diseases: a review.
Acta geneticae medicae et gemellologiae - 1 Jan 1994
Tiberio G
Abstract excerpt
The 20 reported cases of MZ female twins discordant for X-linked diseases are reviewed. In such twins the X-inactivation pattern is opposite skewing (abnormal allele inactivated in most cells of the normal twin, and normal allele inactivated in most cells of the affected twin) or skewing in one t...
Topics
- Color Vision Defects
- Diseases in Twins
- Dosage Compensation, Genetic
- Fabry Disease
- Female
- Fragile X Syndrome
- Genetic Diseases, Inborn
- Glucosephosphate Dehydrogenase Deficiency
- Hemophilia B
- Humans
- Karyotyping
- Models, Genetic
- Mucopolysaccharidosis II
- Muscular Dystrophies
- Phenotype
- Twins, Monozygotic
- X Chromosome