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Article

Impaired dendritic cell differentiation and maturation in the absence of C3.

Molecular immunology - 1 Apr 2008

Reis Edimara S, Barbuto J A M, Köhl Jörg, Isaac Lourdes

Abstract excerpt

Human monocytes can be differentiated into immature dendritic cells (DCs) in the presence of serum and cytokines. One of the main functions of immature DCs is to capture and process antigens. Following maturation, they differentiate into antigen presenting cells. The role of complement in the differentiation process from monocytes towards immature DCs remains elusive. Here we demonstrate that complement 3 (C3)...

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Identifiers

PMID: 18061265
DOI: 10.1016/j.molimm.2007.10.031

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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