Article
Dendritic cells differentiated from human monocytes through a combination of IL-4, GM-CSF and IFN-gamma exhibit phenotype and function of blood dendritic cells.
Advances in experimental medicine and biology - 1 Jan 1995
Xu H, Krämer M, Spengler H P, Peters J H
Abstract excerpt
Our previous studies demonstrated that monocytes, when cultured under certain conditions, are able to differentiate into DC-like cells (MoDC) presenting a high accessory activity and low phagocytic function. In the present study, we demonstrate that under the effect of a triple combination of IL-...
Topics
- Cell Differentiation
- Dendritic Cells
- Granulocyte-Macrophage Colony-Stimulating Factor
- HLA-DR Antigens
- Humans
- In Vitro Techniques
- Interferon-gamma
- Interleukin-4
- Lipopolysaccharide Receptors
- Lymphocyte Activation
- Lymphocyte Culture Test, Mixed
- Monocytes
- Phagocytosis
- Phenotype
- Receptors, IgG
- T-Lymphocytes