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Article

C-type inactivation controls recovery in a fast inactivating cardiac K+ channel (Kv1.4) expressed in Xenopus oocytes.

The Journal of physiology - 15 Dec 1995

Rasmusson R L, Morales M J, Castellino R C, Zhang Y, Campbell D L, Strauss H C

Abstract excerpt

1. A fast inactivating transient K+ current (FK1) cloned from ferret ventricle and expressed in Xenopus oocytes was studied using the two-electrode voltage clamp technique. Removal of the NH2-terminal domain of FK1 (FK1 delta 2-146) removed fast inactivation consistent with previous findings in Kv1.4 channels. The NH2-terminal deletion mutation revealed a slow inactivation process, which matches the criteria for...

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Source

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Identifiers

PMID: 8788936
DOI: 10.1113/jphysiol.1995.sp021085
PMCID: PMC1156841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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