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Article

Effects of marker information on sib-pair linkage analysis of a rare disease.

Genetic epidemiology - 1 Jan 1995

Korczak J F, Pugh E W, Premkumar S, Guo X, Elston R C, Bailey-Wilson J E

Abstract excerpt

Model-free sib-pair linkage analysis was used to screen the GAW9-Problem 1 data set for evidence of linkage of a rare disease to any of 360 highly polymorphic marker loci. Negative regressions nominally significant at the alpha = 0.05 level were obtained for 44 markers; however all of these proved to be Type I errors. None of the four disease loci were detected by sib-pair linkage, which was not surprising, given...

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Identifiers

PMID: 8787984
DOI: 10.1002/gepi.1370120617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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