Article
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair.
Nature genetics - 1 Sept 1996
Risinger J I, Umar A, Boyd J, Berchuck A, Kunkel T A, Barrett J C
Abstract excerpt
Many human tumours have length alterations in repetitive sequence elements. Although this microsatellite instability has been attributed to mutations in four DNA mismatch repair genes in hereditary nonpolyposis colorectal cancer (HNPCC) kindreds, many sporadic tumours exhibit instability but no detectable mutations in these genes. It is therefore of interest to identify other genes that contribute to this...
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