Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation screening of mismatch repair gene Mlh3 in familial esophageal cancer.

World journal of gastroenterology - 7 Sept 2006

Liu Hong-Xu, Li Yu, Jiang Xue-Dong, Yin Hong-Nian, Zhang Lin, Wang Yu, Yang Jun

Abstract excerpt

AIM: To shed light on the possible role of mismatch repair gene Mlh3 in familial esophageal cancer (FEC). METHODS: A total of 66 members from 10 families suggestive of a genetic predisposition to hereditary esophageal cancer were screened for germline mutations in Mlh3 with denaturing high performance liquid chromatography (DHPLC), a newly developed method of comparative sequencing based on heteroduplex...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Esophageal Neoplasms

Share to Family Health

Share to Gene Expression Regulation, Neoplastic

Share to MutL Proteins

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 16981255
DOI: 10.3748/wjg.v12.i33.5281
PMCID: PMC4088192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation screening of mismatch repair gene Mlh3 in familial esophageal cancer.PMID 16981255Read ↗

The first functional study of <i>MLH3</i> mutations found in cancer patientsSemantic proximity Read ↗

Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: Evidence for somatic mutation in colorectal cancers.Semantic proximity Read ↗

MLH3 mutation in endometrial cancer.Semantic proximity Read ↗

A role for MLH3 in hereditary nonpolyposis colorectal cancer.Semantic proximity Read ↗

MUTYH association with esophageal adenocarcinoma in a Han Chinese population.Semantic proximity Read ↗

MSH3: a confirmed predisposing gene for adenomatous polyposis.Semantic proximity Read ↗

Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair.Semantic proximity Read ↗

Association of low-risk MSH3 and MSH2 variant alleles with Lynch syndrome: probability of synergistic effects.Semantic proximity Read ↗

Aberrant methylation of the MSH3 promoter and distal enhancer in esophageal cancer patients exposed to first-hand tobacco smokeSemantic proximity Read ↗

Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

The role of hMLH3 in familial colorectal cancer.Semantic proximity Read ↗

Little evidence for involvement of MLH3 in colorectal cancer predisposition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.