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Article

MLH3 mutation in endometrial cancer.

Cancer research - 1 Aug 2006

Taylor Nicholas P, Powell Matthew A, Gibb Randall K, Rader Janet S, Huettner Phyllis C, Thibodeau Stephen N, Mutch David G, Goodfellow Paul J

Abstract excerpt

MLH3 is a recently described member of the DNA mismatch repair gene family. Based on its interaction with the MutL homologue MLH1, it was postulated that MLH3 might play a role in tumorigenesis. Germ line and somatic mutations in MLH3 have been identified in a small fraction of colorectal cancers, but the role of MLH3 in colorectal cancer tumorigenesis remains controversial. We investigated MLH3's role in...

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Topics

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Share to Carrier Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometrial Neoplasms

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Source

Identifiers

PMID: 16885347
DOI: 10.1158/0008-5472.CAN-06-0248

Genes

MLH3
MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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