Article
Cigarette smoking and p53 mutations in lung cancer and bladder cancer.
Environmental health perspectives - 1 May 1996
Husgafvel-Pursiainen K, Kannio A
Abstract excerpt
We report here a compilation of p53 mutation results from two smoking-related cancers, lung cancer and bladder cancer. The overall mutation frequencies reported for these two types of cancer were relatively similar--50% in lung cancer and 40% in bladder cancer. The compiled data from lung cancer and bladder cancer suggest an increasing proportion of patients with p53 mutations in nonsmokers, former smokers, and...
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