Article
An Mse I RFLP in the human CTLA4 promotor.
Biochemical and biophysical research communications - 23 Aug 1996
Deichmann K, Heinzmann A, Brüggenolte E, Forster J, Kuehr J
Abstract excerpt
We present a PCR-based Mse I restriction fragment length polymorphism (RFLP) in the promotor of the human CTLA4 gene at position -318 relative to the ATG start codon. In a random caucasian population including 239 individuals the allele frequency of the polymorphism was 13.4%, with a calculated heterozygosity rate of 23.2% and an observed one of 25.1%. CTLA4 and CD28 are two genes in close proximity on the long...
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