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Article

CD80 and CD86 polymorphisms in populations of various ancestries: 5 new CD80 promoter alleles.

Human immunology - 1 Jan 2012

Beltrame Márcia Holsbach, Pincerati Márcia Regina, Dalla-Costa Ricardo, Wassem Roseli, Köhler Karen Francine, Chautard-Freire-Maia Eleidi Alice, Tsuneto Luiza Tamie, Petzl-Erler Maria Luiza

Abstract excerpt

CD80 and CD86 are closely linked genes on chromosome 3 that code for glycoproteins of the immunoglobulin superfamily, expressed on the surface of antigen-presenting cells. These costimulatory molecules play essential roles for stimulation and inhibition of T cells through binding to CD28 and CTLA-4 receptors. In this study, CD80 promoter and CD86 exon 8 polymorphisms were analyzed to investigate the genetic...

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PMID: 22074996
DOI: 10.1016/j.humimm.2011.10.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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