Article
Gastric lesions in transforming growth factor beta-1 heterozygous mice.
Laboratory investigation; a journal of technical methods and pathology - 1 Feb 1996
Boivin G P, Molina J R, Ormsby I, Stemmermann G, Doetschman T
Abstract excerpt
Transforming growth factor beta-1 (TGF beta 1) is known to inhibit the growth of many epithelial cell types in culture. Consequently, it is important to determine whether it has any tumor suppressor activity in vitro. Fifteen heterozygous and eight wild type TGF beta 1-deficient mice were examined to determine if there was a difference in lifespan or lesion development due to the loss of one TGF beta 1 allele....
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