Overexpression of transforming growth factor-alpha alters differentiation of gastric cell lineages.

doi:10.1007/BF02213134

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Overexpression of transforming growth factor-alpha alters differentiation of gastric cell lineages.

Digestive diseases and sciences - 1 Apr 1996

Goldenring J R, Ray G S, Soroka C J, Smith J, Modlin I M, Meise K S, Coffey R J

Abstract excerpt

Overexpression of transforming growth factor-alpha (TGF-alpha) in the gastric fundic mucosa of metallothionein promoter/enhancer-TGF-alpha(MT-TGF-alpha) transgenic mice produces a phenotype of foveolar hyperplasia similar to that observed in Ménétrier's disease. We have investigated the dynamics...

Topics

Animals
Cadmium
Cadmium Compounds
Cell Count
Cell Differentiation
Female
Gastric Mucosa
Gastritis, Hypertrophic
Gene Expression
Immunohistochemistry
Male
Mice
Mice, Transgenic
Parietal Cells, Gastric
Phenotype
Sulfates
Transforming Growth Factor alpha

Source

Open in PubMed

Identifiers

PMID: 8674399
DOI: 10.1007/BF02213134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8674399-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics