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Article

Overexpression of transforming growth factor-alpha alters differentiation of gastric cell lineages.

Digestive diseases and sciences - 1 Apr 1996

Goldenring J R, Ray G S, Soroka C J, Smith J, Modlin I M, Meise K S, Coffey R J

Abstract excerpt

Overexpression of transforming growth factor-alpha (TGF-alpha) in the gastric fundic mucosa of metallothionein promoter/enhancer-TGF-alpha(MT-TGF-alpha) transgenic mice produces a phenotype of foveolar hyperplasia similar to that observed in Ménétrier's disease. We have investigated the dynamics involved in the alterations of gastric mucosal morphology in the MT-TGF-alpha mouse model. The fundic mucosa of...

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Identifiers

PMID: 8674399
DOI: 10.1007/BF02213134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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