Article
No association between apolipoprotein E alleles and olivopontocerebellar atrophy.
Journal of the neurological sciences - 11 Jun 1998
Toji H, Kawakami H, Kawarai T, Nakayama T, Komure O, Kuno S, Nakamura S
Abstract excerpt
Apolipoprotein E (apo E) epsilon4 is a risk factor for sporadic and late-onset familial Alzheimer's disease, but it is not well known whether the apo E is associated with spinocerebellar degeneration. We studied the frequency of apo E allele in 59 olivopontocerebellar atrophy (OPCA) patients, including 13 pathologically confirmed cases. The distribution of the apo E allele frequency did not differ between OPCA...
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