Article
Apolipoprotein E allelic frequencies in patients with lobar atrophy.
Neuroscience letters - 31 Mar 1995
Pickering-Brown S M, Siddons M, Mann D M, Owen F, Neary D, Snowden J S
Abstract excerpt
Apolipoprotein E (ApoE) genotype was determined by polymerase chain reaction amplification and restriction digestion of DNA extracted from brain tissues of 26 patients with clinically diagnosed and pathologically verified lobar atrophy (LA) and from blood of a further 22 patients with clinical LA. Brain tissue from 50 patients with pathologically confirmed Alzheimer's disease (AD) was also examined. As has been...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Apolipoproteins E
- Atrophy
- Autopsy
- Dementia
- Frontal Lobe
- Humans
- Middle Aged
