Article
The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway.
Gene - 11 Mar 1994
Lai M H, Bard M, Pierson C A, Alexander J F, Goebl M, Carter G T, Kirsch D R
Abstract excerpt
The Saccharomyces cerevisiae ERG24 gene, encoding sterol delta 14 reductase (Erg24p), was cloned by selecting strains carrying sequences on a 2 mu-based vector for resistance to the morpholine fungicide, fenpropimorph (Fp). Four distinct plasmid inserts which conferred Fp resistance (FpR) were recovered (plasmids pML99, pML100, pML101 and pM103). Although Fp is reported to inhibit activity of Erg24p and sterol...
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