Article
Linkage analysis between pericentrometric markers on chromosome 18 and bipolar disorder: a replication test.
Psychiatry research - 29 Nov 1995
Maier W, Hallmayer J, Zill P, Bondy B, Lichtermann D, Ackenheil M, Minges J, Wildenauer D
Abstract excerpt
Replication was attempted of a recent report on linkage between bipolar affective disorder and pericentrometric loci on chromosome 18. Linkage to these markers was excluded in a sample of five extended multiplex families using lod-score and affected-pedigree-member methods. In one family, however...
Topics
- Adult
- Aged
- Bipolar Disorder
- Centromere
- Chromosome Mapping
- Chromosomes, Human, Pair 18
- Depressive Disorder
- Female
- Gene Frequency
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Male
- Middle Aged
- Models, Genetic
- Pedigree
- Phenotype