Article
Linkage analysis between pericentrometric markers on chromosome 18 and bipolar disorder: a replication test.
Psychiatry research - 29 Nov 1995
Maier W, Hallmayer J, Zill P, Bondy B, Lichtermann D, Ackenheil M, Minges J, Wildenauer D
Abstract excerpt
Replication was attempted of a recent report on linkage between bipolar affective disorder and pericentrometric loci on chromosome 18. Linkage to these markers was excluded in a sample of five extended multiplex families using lod-score and affected-pedigree-member methods. In one family, however, the lod score exceeded 1.0. Although the proposed susceptibility genes are unlikely to have a major impact on the...
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