Article
HLA-DRB1 molecules and antigenic experience shape the repertoire of CD4 T cells.
Human immunology - 1 Dec 1995
Walser-Kuntz D R, Weyand C M, Fulbright J W, Moore S B, Goronzy J J
Abstract excerpt
Forces influencing the composition of the mature TCR repertoire have been well studied in the mouse. In particular, the contribution of MHC molecules in negative and positive selection events of T lymphocytes has been established. To understand whether the allelic polymorphism of HLA-DRB1 molecul...
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