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Article

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

European journal of immunology - 1 Jul 1996

Krakowski M, Owens T

Abstract excerpt

In experimental allergic encephalomyelitis (EAE), T cells infiltrate the central nervous system (CNS) and induce inflammation. These CD4+ T cells secrete interferon (IFN)-gamma, levels of which correlate with disease severity, and which is proposed to play a key role in disease induction. Many strains of mice are resistant to EAE. We have studied the effect of deletion of IFN-gamma on the ability to induce EAE in...

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Source

Identifiers

PMID: 8766573
DOI: 10.1002/eji.1830260735

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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