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Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers.

Japanese journal of cancer research : Gann - 1 Jun 1996

Akiyama Y, Nakasaki H, Nihei Z, Iwama T, Nomizu T, Utsunomiya J, Yuasa Y

Abstract excerpt

Microsatellite instability or replication error seems to be related to defective DNA mismatch repair genes, such as hMSH2, hMLH1, hPMS1 and hPMS2, which have been identified as causative genes of hereditary nonpolyposis colorectal cancers (HNPCC). Recently, it was reported that mutations at the simple repeated sequences in the transforming growth factor-beta type II receptor (TGF-beta RII) gene occurred in...

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Identifiers

PMID: 8766523
DOI: 10.1111/j.1349-7006.1996.tb00265.x
PMCID: PMC5921144

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Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers.PMID 8766523Read ↗

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Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 in Japanese hereditary nonpolyposis colorectal cancer kindreds.Semantic proximity Read ↗

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Microsatellite instability in gastric cancer prone families.Semantic proximity Read ↗

Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers.Semantic proximity Read ↗

Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas.Semantic proximity Read ↗

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