Article
Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers.
Japanese journal of cancer research : Gann - 1 Jun 1996
Akiyama Y, Nakasaki H, Nihei Z, Iwama T, Nomizu T, Utsunomiya J, Yuasa Y
Abstract excerpt
Microsatellite instability or replication error seems to be related to defective DNA mismatch repair genes, such as hMSH2, hMLH1, hPMS1 and hPMS2, which have been identified as causative genes of hereditary nonpolyposis colorectal cancers (HNPCC). Recently, it was reported that mutations at the s...
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