Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

α2β1 Integrin Regulates Lineage Commitment in Multipotent Human Colorectal Cancer Cells*

30 Jul 2008

Abstract excerpt

The human colorectal epithelium is maintained by multipotent stem cells that give rise to absorptive, mucous, and endocrine lineages. Recent evidence suggests that human colorectal cancers are likewise maintained by a minority population of so-called cancer stem cells. We have previously established a human colorectal cancer cell line with multipotent characteristics (HRA-19) and developed a serum-free medium...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caveolin-1 and cellular processes
Share to Cell Adhesion Molecules Research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18664572
DOI: 10.1074/jbc.m802932200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

α2β1 Integrin Regulates Lineage Commitment in Multipotent Human Colorectal Cancer Cells*PMID 18664572Read ↗

Multilineage differentiation of cloned HRA-19 cells in serum-free medium: a model of human colorectal epithelial differentiation.Semantic proximity Read ↗

The expression of cancer stem cell markers in human colorectal carcinoma cells in a microenvironment dependent mannerSemantic proximity Read ↗

Human Intestinal Epithelial Cell Survival and AnoikisSemantic proximity Read ↗

Oncogenic Ki-ras but not oncogenic Ha-ras blocks integrin beta1-chain maturation in colon epithelial cells.Semantic proximity Read ↗

Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cellsSemantic proximity Read ↗

Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line.Semantic proximity Read ↗

ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogationSemantic proximity Read ↗

Intestinal stem cells and the colorectal cancer microenvironment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.