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Article

A matter of differentiation: equine enteroids as a model for the in vivo intestinal epithelium

16 Mar 2024

Abstract excerpt

Epithelial damage due to gastrointestinal disorders frequently causes severe disease in horses. To study the underlying pathophysiological processes, we aimed to establish equine jejunum and colon enteroids (eqJE, eqCE) mimicking the in vivo epithelium. Therefore, enteroids were cultivated in four different media for differentiation and subsequently characterized histomorphologically, on mRNA and on protein level...

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PMID: 38493107
DOI: 10.1186/s13567-024-01283-0

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