Article
Mutation of low affinity nerve growth factor receptor gene is associated with the hypertensive phenotype in spontaneously hypertensive inbred rat strains.
Neuroscience letters - 24 May 1996
Nemoto K, Kageyama H, Ueyama T, Fukamachi K, Sekimoto M, Tomita I, Senba E, Forehand C J, Hendley E D
Abstract excerpt
We previously reported a missense mutation in the low affinity nerve growth factor receptor (LNGFR) gene of spontaneously hypertensive rats (SHR), proposing this gene as a promising candidate in genetic hypertension. In this study we provide further support for implicating this gene in genetic hy...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Behavior, Animal
- Blood Vessels
- Hypertension
- Molecular Sequence Data
- Nerve Growth Factors
- Phenotype
- Point Mutation
- RNA, Messenger
- Rats
- Rats, Inbred SHR
- Rats, Inbred WKY
- Receptors, Nerve Growth Factor