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Article

Functional alterations of the Nppa promoter are linked to cardiac ventricular hypertrophy in WKY/WKHA rat crosses.

Circulation research - 2 Feb 2001

Deschepper C F, Masciotra S, Zahabi A, Boutin-Ganache I, Picard S, Reudelhuber T L

Abstract excerpt

Cardiac left ventricular hypertrophy (LVH) is commonly associated with hypertension, but its variance is determined for more than 50% by blood pressure-independent genetic factors. Because it constitutes one of the most important risk factors for cardiovascular mortality, we have performed a genome-wide scan of the F2 progeny of crosses between inbred WKY and WKHA rats to detect quantitative trait loci (QTL)...

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Share to Atrial Natriuretic Factor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertrophy, Left Ventricular

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Share to Rats, Inbred WKY

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Source

Identifiers

PMID: 11157676
DOI: 10.1161/01.res.88.2.223

Genes

NPPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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