Article
Nerve growth factor gene and hypertension in spontaneously hypertensive rats.
Journal of hypertension - 1 Feb 1996
Kapuscinski M, Charchar F, Innes B, Mitchell G A, Norman T L, Harrap S B
Abstract excerpt
OBJECTIVE: High blood pressure in spontaneously hypertensive rat (SHR) is associated with increased sympathetic innervation of key tissues, possibly as the result of increased nerve growth factor (NGF). The aim of this study was to test for genetic linkage of the NGF gene to high blood pressure. DESIGN: We studied NGF gene expression in young SHR and examined linkage of the NGF locus to mean arterial pressure in...
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