Article
Sigma factor-anti-sigma factor interaction in alginate synthesis: inhibition of AlgT by MucA.
Journal of bacteriology - 1 Aug 1996
Xie Z D, Hershberger C D, Shankar S, Ye R W, Chakrabarty A M
Abstract excerpt
Conversion from the nonmucoid to the mucoid phenotype is a typical feature of Pseudomonas aeruginosa strains causing chronic pulmonary infections in cystic fibrosis patients. One of the key genetic controls in this conversion to mucoidy is from the algT(U)-mucA-mucB(algN) locus, located at 67.5 min on the standard P. aeruginosa chromosomal map. The algT gene promotes conversion to mucoidy and encodes an...
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