Article
Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress response.
Journal of bacteriology - 1 Nov 1994
Martin D W, Schurr M J, Yu H, Deretic V
Abstract excerpt
Alginate overproducition by mucoid Pseudomonas aeruginosa is a critical pathogenic determinant expressed by this organism during chronic infections in cystic fibrosis. Conversion to mucoidy and a subsequent loss of mucoid character can occur via different mutations in the algU mucA mucB gene clus...
Topics
- Adaptation, Physiological
- Alginates
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Carbohydrate Dehydrogenases
- Genes, Bacterial
- Models, Genetic
- Molecular Sequence Data
- Morphogenesis
- Multigene Family
- Phenotype
- Promoter Regions, Genetic
- Pseudomonas aeruginosa