Transfection of human estrogen receptor (ER) cDNA into ER-negative mammalian cell lines.

doi:10.1016/0960-0760(94)90035-3

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Article

Transfection of human estrogen receptor (ER) cDNA into ER-negative mammalian cell lines.

The Journal of steroid biochemistry and molecular biology - 1 Dec 1994

Levenson A S, Jordan V C

Abstract excerpt

Estrogen responsiveness of breast tumors can be correlated with the presence or absence of the estrogen receptor (ER). Breast cancer cells that contain ER are, in general, responsive to stimulation by estrogen both in vivo and in vitro; therefore hormonal control is possible. Breast tumors that l...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Division
Cell Line
DNA, Complementary
Estrogens
Gene Expression Regulation
Humans
Molecular Sequence Data
Mutation
Receptors, Estrogen
Transfection

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